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Benjamin Thoreau։ Highlighting the Burden and Heterogeneity of ILD in ANCA-Associated Vasculitis
Benjamin Thoreau/LinkedIn
Feb 14, 2026, 16:03

Benjamin Thoreau։ Highlighting the Burden and Heterogeneity of ILD in ANCA-Associated Vasculitis

Benjamin Thoreau, Hospital Practitioner at CHRU Tours (Hospital), shared a post on LinkedIn about a recent article by Aglaia Chalkia et al, published in American College of Rheumatology:

”Interstitial Lung Disease in ANCA-Associated Vasculitis: A European Multicentre Study

A large retrospective European study highlights the burden and heterogeneity of ILD in AAV:

  • 162 MPO-ANCA+ patients (85%)
  • AAV-ILD: 76% | Isolated ANCA-ILD: 24%
  • UIP most frequent pattern (57%)
  • Renal involvement: 73%

Lung function trajectories differed by radiological pattern, with greater annual FVC decline in UIP/NSIP. Age and baseline FVC% independently predicted mortality, while respiratory failure correlated with fibrosis severity and initial FVC.

Important data to better phenotype and stratify prognosis in AAV-ILD.”

Title: Interstitial Lung Disease in ANCA-Associated Vasculitis: A European Multicentre Study

Authors: Aglaia Chalkia, Marusa Kotnik, Timothy J Sadler, Spyridon Katechis, Rachel Jones, Ajay Kamath, Aladdin J Mohammad, Sara Monti, Chetan Mukhtyar, Viral Nanda, Ioannis Petrakis, Dimitrios Petras, Ashnish Sinha, Pasupathy Sivasothy, Rona Smith, Kostas Stylianou, Dimitrios Vassilopoulos, Judith Babar, David Jayne

Read the Full Article on American College of Rheumatology.

Benjamin Thoreau։ Highlighting the Burden and Heterogeneity of ILD in ANCA-Associated Vasculitis

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Aglaia Chalkia Ajay Kamath Aladdin J Mohammad American College of Rheumatology Ashnish Sinha Benjamin Thoreau Chetan Mukhtyar David Jayne Dimitrios Petras Dimitrios Vassilopoulos Hematology Hemostasis Hemostasis News Hemostasis Today Ioannis Petrakis Judith Babar Kostas Stylianou Marusa Kotnik Medicine Pasupathy Sivasothy Rachel Jones Rona Smith Sara Monti Spyridon Katechis thrombosis Timothy J Sadler Viral Nanda
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