Benjamin Thoreau։ Highlighting the Burden and Heterogeneity of ILD in ANCA-Associated Vasculitis
Benjamin Thoreau, Hospital Practitioner at CHRU Tours (Hospital), shared a post on LinkedIn about a recent article by Aglaia Chalkia et al, published in American College of Rheumatology:
”Interstitial Lung Disease in ANCA-Associated Vasculitis: A European Multicentre Study
A large retrospective European study highlights the burden and heterogeneity of ILD in AAV:
- 162 MPO-ANCA+ patients (85%)
- AAV-ILD: 76% | Isolated ANCA-ILD: 24%
- UIP most frequent pattern (57%)
- Renal involvement: 73%
Lung function trajectories differed by radiological pattern, with greater annual FVC decline in UIP/NSIP. Age and baseline FVC% independently predicted mortality, while respiratory failure correlated with fibrosis severity and initial FVC.
Important data to better phenotype and stratify prognosis in AAV-ILD.”
Title: Interstitial Lung Disease in ANCA-Associated Vasculitis: A European Multicentre Study
Authors: Aglaia Chalkia, Marusa Kotnik, Timothy J Sadler, Spyridon Katechis, Rachel Jones, Ajay Kamath, Aladdin J Mohammad, Sara Monti, Chetan Mukhtyar, Viral Nanda, Ioannis Petrakis, Dimitrios Petras, Ashnish Sinha, Pasupathy Sivasothy, Rona Smith, Kostas Stylianou, Dimitrios Vassilopoulos, Judith Babar, David Jayne
Read the Full Article on American College of Rheumatology.
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