Why Do Genetic and Lab Findings Often Mismatch in VTE Anticoagulant Defect Diagnosis?
Journal of Thrombosis and Haemostasis (JTH) shared an insightful post on LinkedIn:
“Genotype vs laboratory phenotype correlation of defects in natural anticoagulants in patients with venous thromboembolism.
In VTE patients, genotype-phenotype concordance for natural anticoagulant defects is far from absolute.
This study reveals that genetic variants may present with normal plasma activity, while reduced activity can occur without detectable variants – underscoring the diagnostic limitations of relying solely on either approach.”
Read the paper here.
Article: Genotype vs laboratory phenotype correlation of defects in natural anticoagulants in patients with venous thromboembolism
Authors: Christine Van Laer, Marthe Vanrenterghem, Marc Jacquemin, Andreas Verstraete, Sarissa Baert, Cyrielle Kint, Mirjam Kruijt, Renee Ruhaak, Veerle Labarque, Thomas Vanassche, Peter Verhamme, Kathelijne peerlinck, Kathleen Freson
Stay updated with Hemostasis Today.
-
May 28, 2026, 09:16Maxime Dely: The Human Connection Behind Stem Cell Donation
-
May 28, 2026, 09:15Heghine Khachatryan: Maternal Health Begins With Recognizing Iron Deficiency Early
-
May 28, 2026, 09:15Alejandro González Veliz: Why Cardiovascular Prevention Matters More Than Intervention
-
May 28, 2026, 05:29Kidist K.: First Balloon Pulmonary Angioplasty Performed as New CTEPH Program Launches
-
May 28, 2026, 04:59Maria Sol Andres: Exploring Lipid Disorders in Modern Cancer Care
-
May 28, 2026, 04:42Francesca Granata: Representing the Porphyria Community at the 79th World Health Assembly
-
May 28, 2026, 04:29Samone Cook: When Collaboration Turns Into Organizational Coagulation
-
May 28, 2026, 03:42Lara Bloom: 15,000 Steps, Countless Conversations – One Unforgettable WHA79
-
May 27, 2026, 23:00Octavio Marques Pontes-Neto: Exchanging Latin American Experiences at the Global Stroke Alliance Meeting in Buenos Aires