Wolfgang Miesbach: Targeted Anti-TFPI Therapy with Marstacimab Supports Joint Stability in Hemophilia A
Wolfgang Miesbach, Professor of Medicine at Frankfurt University Hospital, shared a post on LinkedIn:
”Michael Sigl-Kraetzig and colleagues presented at GTH 2026 in Bonn the first European real-world experience with Marstacimab in a patient with haemophilia A and advanced haemophilic arthropathy.
The poster describes a switch from intravenous factor prophylaxis to subcutaneous anti-TFPI prophylaxis (Marstacimab) in a patient with poor prior adherence, resulting in a lower treatment burden and markedly improved adherence.
Joint status was monitored clinically and by standardised ultrasound (HEAD-US), enabling structured assessment of arthropathy progression.
Following a post-traumatic bleed, treatment was escalated to a doubled Marstacimab dose, with ongoing excellent adherence and no thromboembolic events reported so far.
This case highlights how targeted anti-TFPI therapy, combined with standardised imaging and individualised dose adjustment, may support adherence and help stabilise joint outcomes in haemophilia care.”
Stay updated with Hemostasis Today.
-
Jun 7, 2026, 09:26Filimon Dagnew Bezabih: SNMMI Honors 18F-GP1 PET Imaging for Innovation in Thrombosis Detection
-
Jun 7, 2026, 06:57Chandran Nadarajan: Targeted Endovascular Thrombolysis Offers Organ-Saving Benefits in Vascular Occlusions
-
Jun 7, 2026, 05:50Sayan Koley: Lupus Anticoagulant – A Key Marker in Thrombosis Risk Assessment
-
Jun 7, 2026, 05:45Nicolas Hubacz: Watching a Heart Build Its Network
-
Jun 7, 2026, 05:40New Evidence Highlights the Urgent Need for Gender-Inclusive Bleeding Disorders Research – EHC
-
Jun 7, 2026, 03:15Shirley D’Sa: What Comes After BTK Inhibitors in Waldenström Macroglobulinaemia?
-
Jun 6, 2026, 23:30Yazan Abou-Ismail: Insights on A Snail-Derived Potential Anticoagulant with Possibly Improved Bleeding Profile
-
Jun 6, 2026, 18:40Igor Carvalho de Oliveira: The Hidden Genetic Risk Behind Early Heart Attacks and Strokes
-
Jun 6, 2026, 17:39Kalyan Roy: Immunomodulation after Blood Transfusion