Alexandru Stieber: Large-Vessel Vasculitis – Clinical Patterns and Treatment
Alexandru Stieber, Internal Medicine Resident at SUUMC Bucharest, shared a post on LinkedIn about a recent article by Patrice Cacoub et al., published in The Lancet, adding:
“A very useful review on large-vessel vasculitis (LVV) from The Lancet Group.
From detailing the clinical phenotypes and summarizing the main therapeutic approaches, this review also proves insightful for including ‘isolated aortitis’ as a clinically relevant entity.
- Giant cell arteritis (GCA) – older adults, symmetrical, mostly thoracic aortic involvement (axillary predominantly), polymyalgia rheumatica as the most common association, complicates mostly by anuerysms.
- Takayasu arteritis (TAK) – younger adults, asymmetrical involvement, predominant abdominal vascular involvement, tendency towards stenoses.
- Isolated aortitis – ascending aorta predominantly, seldom constitutional.
Also, the article highlights important secondary etiologies of LVV and/or mimickers, such as infections, iatrogenic scenarios and systemic diseases such as the periaortitis from erdheimchester disease.”
Title: Large-vessel vasculitis
Authors: Patrice Cacoub, Matheus Vieira, Carol A Langford, Zoubida Tazi Mezalek, David Saadoun
Other posts featuring Alexandru Stieber on Hemostasis Today.
-
Oct 8, 2026, 04:28Jeff Molter: Electrophysiological PIEZO1 Analysis Advances Diagnosis in Hereditary Xerocytosis
-
Oct 8, 2026, 04:23Barbara Adams Krolak: Women and Blood Clots Are We Missing the Warning Signs
-
Oct 8, 2026, 04:10Rutendo Muzambi: Hospital Admission Patterns and Care Disparities in Sickle Cell Disease
-
Oct 8, 2026, 03:50Olfat Berro: Redefining the Future of Haemophilia A
-
Oct 8, 2026, 03:35Tasnia Tarana: Heavy Menstrual Bleeding When the Cause Is Not in the Uterus
-
Oct 8, 2026, 03:28Kian Haseli: Electrophysiological PIEZO1 Analysis Advances Diagnosis in Hereditary Xerocytosis
-
Oct 8, 2026, 03:20Sthanu Subramanian: Leukopenia in Sepsis A Marker of Severe Disease
-
Oct 7, 2026, 16:44Amor Salah: 2026 NCS/SCCM Guidelines for Managing Antithrombotic-Associated ICH
-
Oct 7, 2026, 16:04NETs in Thrombosis: From Mechanism to Therapeutic Target