Arianna Giannetti: Ever Wondered If Mechanical Stretch Could Play a Role in DVT?
Arianna Giannetti, Postdoctoral Research Fellow at LadHyX École Polytechnique, shared on LinkedIn:
”Ever wondered if mechanical stretch could play a role in deep vein thrombosis (DVT)?
I am very happy to share that our paper “Uniaxial cyclic stretch regulates the expression of thrombomodulin and von Willebrand factor on endothelial cells” is now published in Blood VTH
During my PhD at the Centre de Biologie Structurale (Université de Montpellier), we explored how mechanical forces shape endothelial behavior.
Our key findings:
1. Continuous 10% cyclic stretch increases antithrombotic Thrombomodulin.
2. Interrupted stretch increases prothrombotic von Willebrand factor.
This suggests that how veins stretch might influence DVT mechanisms more than we thought.
Huge thanks to our amazing collaborators across Bordeaux, Nîmes, and Montpellier
And grateful for support from the ANR Programme Investissements d’Avenir.”
Read the full article here.
Article: Uniaxial cyclic stretch regulates the expression of thrombomodulin and von Willebrand factor on endothelial cells
Authors: Arianna Giannetti, Elisabeth Génot, Antonia Perez-Martin, Elsa Faure, Jean-Christophe Gris, Maïda Cardoso, Christophe Goze-Bac, Christine Benistant, Manouk Abkarian
Stay updated on all scientific advances in the field of thrombosis with Hemostasis Today.
-
Feb 23, 2026, 17:59Wolfgang Miesbach: Real-World Evidence of Emicizumab on Joint Outcomes in Hemophilia A
-
Feb 23, 2026, 17:56Shiny K Kajal: The Transfusion Reaction We Often Miss
-
Feb 23, 2026, 17:53Radheshyam Meher: Contributing to the Transfusion Evidence Round-Up for International Childhood Cancer Day 2026
-
Feb 23, 2026, 17:46Mahesan Subramaniam: The Physiological Impact of Anger on Immunity
-
Feb 23, 2026, 17:42Bryan Fry: First Evidence That Bothrops atrox Venom Directly Activates Human Factor VII
-
Feb 23, 2026, 17:34Bastu Odoka: Why Blood Should NOT be Left at the Bedside to ‘Warm’
-
Feb 23, 2026, 17:28Henry Burkitt: Patients Are Challenging How the Medicines Policy System Works in England
-
Feb 23, 2026, 16:50Mutaz Al‑Sabah: Interesting Webinar on FH in Women is Now Available to Watch
-
Feb 23, 2026, 16:36Stéphanie Roullet։ New Method to Explore Primary Haemostasis in Cirrhotic Patients