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Insights on IV Thrombolysis and Mechanical Thrombectomy from Benjamin Maier and Colleagues
Oct 24, 2025, 11:34

Insights on IV Thrombolysis and Mechanical Thrombectomy from Benjamin Maier and Colleagues

Benjamin Maier, University Professor at Paris Cité University Medicine, shared on LinkedIn:

”Hot from the press!

Everything you always wanted to know about IV thrombolysis and mechanical thrombectomy in acute ischemic stroke… but were too afraid to ask

Two comprehensive reviews we just published in the outstanding Med (Cell Press) journal:

  • IV Thrombolysis, by Dr Hugo Diaz
    A masterful synthesis of 30 years of randomized trials, revisiting alteplase, tenecteplase, reteplase, desmoteplase, and all the other -ases that shaped stroke medicine.
  • Mechanical thrombectomy, by Dr Samuel Mouyal
    A deep dive into 15 years of RCTs, from IMS3 to MR CLEAN, to the latest studies, charting the next frontiers in stroke care: AI-guided strategies, new paradigms, and beyond.

Huge congratulations to Hugo Diaz and Samuel Mouyal for these outstanding contributions!

For the IV Thrombolysis review.

For the mechanical thrombectomy review.”

Article 1: Thirty years of intravenous thrombolysis for acute ischemic stroke: Historical perspectives, evidence from randomized trials, and emerging directions

Authors: Hugo Diaz, Samuel Mouyal, Mathieu Zuber, Claire Join-Lambert, Mikael Mazighi, Jean-Marc Olivot, Benjamin Maïer

Article 2: Endovascular therapy for acute ischemic stroke: From a decade of trials to the next frontier

Authors: Samuel J. Mouyal, Hugo Diaz, Mathieu Zuber, Ruben Tamazyan, Adrien Romulus, Jean-Philippe Desilles, Jean-Marc Olivot, Mikael Mazighi, Benjamin Maïer.

Insights on IV Thrombolysis and Mechanical Thrombectomy from Benjamin Maier and Colleagues

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