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Krishna Aragam and Team Identify CD36 Variant Raising Cardiomyopathy Risk in African Ancestry
Krishna Aragam/LinkedIn
Nov 8, 2025, 01:36

Krishna Aragam and Team Identify CD36 Variant Raising Cardiomyopathy Risk in African Ancestry

Krishna Aragam, Director of Cardiovascular Genomics at Cleveland Clinic, posted on LinkedIn:

”Our Nature Genetics paper describing an African ancestry-specific nonsense variant in CD36 associated with increased risk of dilated cardiomyopathy now has a corresponding Nature Research Briefing — a concise summary highlighting the key findings and broader implications, prepared together with first-author Jennifer Huffman.

[2-page PDF attached]

For the full paper, go here.

And last week’s discussion thread here.”

Title: An African ancestry-specific nonsense variant in CD36 is associated with a higher risk of dilated cardiomyopathy

Authors: Jennifer E. Huffman, Liam Gaziano, Zeina R. Al Sayed, Renae L. Judy, Laura M. Raffield, Kiran J. Biddinger, Brian Charest, Anant Chopra, David Gagnon, Xiuqing Guo, Vera Koledova, Michael G. Levin, Yuan-I Min, James P. Pirruccello, Nosheen Reza, Richard Ruan, Shefali Setia Verma, Bharath Ambale Venkatesh, Anurag Verma, Jie Yao, John Jeffrey Carr, Juan P. Casas, Kelly Cho, Joao A. C. Lima, Wendy S. Post, Daniel J. Rader, Marylyn D. Ritchie, Amil Shah, Kent D. Taylor, James G. Terry, Stephen S. Rich, Christopher J. O’Donnell, Lawrence S. Phillips, Kathryn L. Lunetta, Jerome I. Rotter, Peter W. F. Wilson, J. Michael Gaziano, Scott M. Damrauer, VA Million Veteran Program, Yan V. Sun, Patrick T. Ellinor, Jacob Joseph, Krishna G. Aragam

Krishna Aragam and Team Identify CD36 Variant Raising Cardiomyopathy Risk in African Ancestry Cardiomyopathy

 

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African Ancestry Amil Shah Anant Chopra Anurag Verma Bharath Ambale Venkatesh Brian Charest Cardiology cardiomyopathy Cardiovascular Genomics CD36 Christopher J. O’Donnell Cleveland Clinic Daniel J. Rader David Gagnon Dilated Cardiomyopathy Health Hematology Hemostasis Hemostasis Today J. Michael Gaziano Jacob Joseph James G. Terry James P. Pirruccello Jennifer E. Huffman Jerome I. Rotter Jie Yao Joao A. C. Lima John Jeffrey Carr Juan P. Casas Kathryn L. Lunetta Kelly Cho Kent D. Taylor Kiran J. Biddinger Laura M. Raffield Lawrence S. Phillips Liam Gaziano Marylyn D. Ritchie Medicine Michael G. Levin Nature Nature Genetics Nature Research Briefing Nosheen Reza Patrick T. Ellinor Peter W. F. Wilson Renae L. Judy Richard Ruan Scott M. Damrauer Shefali Setia Verma Stephen S. Rich thrombosis VA Million Veteran Program Vera Koledova Wendy S. Post Xiuqing Guo Yan V. Sun Yuan-I Min Zeina R. Al Sayed
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