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Erwin Loh: Triple Combination Therapy Shows Major Benefit in Preventing Recurrent Stroke
Apr 24, 2026, 17:58

Erwin Loh: Triple Combination Therapy Shows Major Benefit in Preventing Recurrent Stroke

Erwin Loh, President of Royal Australasian College of Medical Administrators, shared a post on LinkedIn about a recent article by The Trident Research Group, published in The New England Journal of Medicine:

Low-dose triple-pill cut risk of recurrent stroke by about 40 percent, global trial shows

Patients treated with 3-in-1 blood pressure pill experienced a third less major adverse cardiovascular events.

Treatment with GMRx2, a single pill combination of three low-dose blood pressure medicines, significantly reduced the risk of another stroke in patients with intracerebral haemorrhage and high blood pressure.

Results from the TRIDENT randomised controlled trial, led by The George Institute for Global Health, were published today in The New England Journal of Medicine.

Source in comments.”

Title: Three Low-Dose Antihypertensive Agents in a Single Pill after Intracerebral Hemorrhage

Author: Craig S. Anderson, Clara K. Chow, H. Asita de Silva, Bimsara Senanayake, Kolawole Wahab, Rustam Al-Shahi Salman, Catharina J.M. Klijn, Sheila Ouriques Martins, Natalie Espinosa, Lauren Kuhles, Laurent Billot, Hisatomi Arima, Cheryl Carcel, Xia Wang, Qiang Li, Sana Shan, Mathangi Shanthakumar, Huy Thang Nguyen, Dilum Palliyaguruge, Janaka Peiris, Udaya K. Ranawaka, Senaka Bandusena, Thambipillai Rajendiran, Darshana Wijegunasinghe, Harsha Gunasekera, Indunil Wijeweera, Athula Dissanayake, Ajantha Keshavaraj, Reginald O. Obiako, Rufus Akinyemi, Luiz Nasi, Rodrigo Bazan, Carla Heloisa Cabral Moro, Mariana Battaglini, Viviane Zétola, Wan Chung Law, Yuen Kang Chia, Dennis Cordato, Rohan Grimley, Anuradha Dahanayaka, Sonali Liyanagamage, Nilukshi Fernando, Nihara Abdul Rasheed, Nodar Kakabadze, Maia Beridze, Mythily Aravinthan, Vithoosan Sahathevan, Devasmitha Wijesundara, Pramith Ruwanpathirana, Wan Asyraf Wan Zaidi, Tinatin Kherkheulidze, Urs Fischer, Ana Cláudia de Souza, Tsong-Hai Lee, Christopher Chen, Octavio Pontes-Neto, Thompson Robinson, Jiguang Wang, Sharon L. Naismith, Michael Barnett, Carlos Delfino, Shoujiang You, Feifeng Liu, Candice Delcourt, Tom J. Moullaali, Tim Wilkinson, Neil Watson, Karla Santo, Qiao Han, Mariana Almudi Souza, Wilmar M.T. Jolink, Anderson Berni Cristofari, Zien Zhou, Floris H. Schreuder, Richard I. Lindley, Manuela Armenis, Mark Woodward, Ruth Freed, Lili Song, John Chalmers, Anthony Rodgers

Erwin Loh: Triple Combination Therapy Shows Major Benefit in Preventing Recurrent Stroke

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