First author of the article - Ali Aftabjahani/LinkedIn
May 25, 2026, 05:04
Fibrinogen αC Domain Lysines Drive Plasminogen Binding and Plasmin Generation – JTH
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn about a recent article by Ali Aftabjahani et al, adding:
”The Fibrinogen αC Domain Binds Plasminogen and Enhances Plasmin Generation on Thrombin-Activated Platelets
This study reveals that C-terminal lysine residues in fibrinogen’s αC domain are critical for maximal plasminogen binding and plasmin generation on activated platelets, a process suppressible by TAFIa.”
Title: The Fibrinogen αC Domain Binds Plasminogen and Enhances Plasmin Generation on Thrombin-Activated Platelets
Authors: Ali Aftabjahani, Chengliang (Chris) Wu, Matthew Flick, Peter Gross, Paul Kim
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