HbA1c Reduction, Not Weight Loss, Drives GLP-1RA Heart Benefits
Emma Harutyunyan, Endocrinologist at Yeolyan Hematology and Oncology Center, shared a post by Daisuke Yabe on LinkedIn:
”HbA1c reduction, not bodyweight change, was significantly and proportionally associated with MACE risk reduction.
HbA1c lowering may serve as a useful surrogate for the cardiovascular improvements associated with GLP-1RAs in type 2 diabetes.”
Quoting Daisuke Yabe‘s post:
”FYI”
Title: Cardiovascular risk reduction with glucagon-like peptide-1 receptor agonists is proportional to HbA1c lowering in type 2 diabetes: An updated meta-regression analysis incorporating FLOW and SOUL trials
Authors: Masashi Hasebe, Chen-Yang Su, Yamato Keidai, Hiroto Minamino, Daisuke Yabe, Nobuya Inagaki, Satoshi Yoshiji
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