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Irma Bagdoniene: From Estimating Risk to Seeing Disease in Preventive Cardiology
Irma Bagdoniene/LinkedIn
Feb 12, 2026, 16:04

Irma Bagdoniene: From Estimating Risk to Seeing Disease in Preventive Cardiology

Irma Bagdoniene, Cardiologist Specializing in Prevention and Lipidology, shared a post on LinkedIn about a recent article by Kenrick Schulze et al, published in Nature Reviews Cardiology:

”Are we still estimating risk when we can actually see it?

In preventive cardiology, risk used to be something we calculated.

Today, with coronary CT angiography, it is something we can see.

CCTA reveals both calcified and soft plaque — the atherosclerosis that traditional risk scores cannot capture. Registry data from confirm, advance, and decide show that plaque burden and high-risk plaque features predict events better than calcium score or stenosis alone, especially in patients who live in the preventive ‘gray zone’.

Instead of reacting to events, we can identify disease early and personalize preventive therapy based on the plaque we observe within the vessel wall.

To prevent myocardial infarction, we must move from estimating risk to treating the disease we can now visualize.

Title: Coronary CT angiography evaluation with artificial intelligence for individualized medical treatment of atherosclerosis: a Consensus Statement from the QCI Study Group

Authors: Kenrick Schulze, Anne-Marieke Stantien, Michelle C. Williams, Vassilios S. Vassiliou, Andreas A. Giannopoulos, Koen Nieman, Pál Maurovich-Horvat, Jason M. Tarkin, Rozemarijn Vliegenthart, Jonathan Weir-McCall, Mahmoud Mohamed, Bernhard Föllmer, Federico Biavati, Ann-Christine Stahl, Jakob Knape, Hanna Balogh, Nicola Galea, Ivana Išgum, Armin Arbab-Zadeh, Hatem Alkadhi, Robert Manka, David A. Wood, Edward D. Nicol, Nick S. Nurmohamed, Fabrice M. A. C. Martens, Damini Dey, David E. Newby, Marc Dewey

Read the Full Article on Nature Reviews Cardiology․

Irma Bagdoniene: From Estimating Risk to Seeing Disease in Preventive Cardiology

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Andreas A. Giannopoulos Ann-Christine Stahl Anne-Marieke Stantien Armin Arbab-Zadeh Bernhard Föllmer Damini Dey David A. Wood David E. Newby Edward D. Nicol Fabrice M. A. C. Martens Federico Biavati Hanna Balogh Hatem Alkadhi Irma Bagdoniene Ivana Išgum Jakob Knape Jason M. Tarkin Jonathan Weir-McCall Kenrick Schulze Koen Nieman Mahmoud Mohamed Marc Dewey Michelle C. Williams Nick S. Nurmohamed Nicola Galea Pál Maurovich-Horvat Robert Manka Rozemarijn Vliegenthart Vassilios S. Vassiliou
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