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November, 2026
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Irma Bagdoniene: What Really Makes Us Live Longer
Nov 9, 2026, 12:49

Irma Bagdoniene: What Really Makes Us Live Longer

Irma Bagdoniene, Cardiologist specializing in Lipidology and Cardiovascular Prevention , shared a post on LinkedIn about a recent article by Diana Romenskaja-Avgul et al, published in Nature, adding:

“Can we really buy longevity? Or are we just buying expensive promises?

NADplus boosters, NMN supplements, anti aging therapies…

The longevity industry is booming. But does increasing a biomarker actually mean living longer?

A fascinating new study published in Nature Metabolism, involving 1,068 adults, challenges a popular assumption:

Whole blood NAD levels do NOT necessarily decline with age.

In healthy men, they remained stable. In healthy women, they actually increased with age!

This brings me back to LDL cholesterol.

We have decades of evidence that lowering LDL cholesterol reduces cardiovascular events. We know that cumulative LDL exposure drives atherosclerosis. And we have therapies with proven clinical benefits.

Yet we sometimes spend hundreds or thousands on longevity products while overlooking the risk factors that actually shorten our lives.

Longevity should be measured in healthy years gained, not in biomarkers improved.

What do you think? Are we investing too much in longevity trends and too little in evidence based prevention?”

Title: Whole-blood NAD levels track cardiovascular disease but not chronological age

Authors: Diana Romenskaja-Avgul, Deimantė Stakelytė, Audrius Laurynėnas, Eimantas Ramonas, Rūta Zabitaitė, Simona Cibulskė, Sigita Danilevičienė, Rapolas Danilevičius, Kristina Ratautė, Marius Dagys, Dalius RatautasIrma Bagdoniene: What Really Makes Us Live Longer

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