Marco Spagnolo: Catheter-Based LAAC vs. Oral Anticoagulation
Marco Spagnolo, Associate Editor at EuroIntervention Case Reports, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in JAMA Cardiology, adding:
“We tried to bring some clarity to the growing body of evidence comparing catheter-based left atrial appendage closure (LAAC) with oral anticoagulation (OAC) for stroke prevention in patients with atrial fibrillation.
Beyond the numerical results summarized in this slide, I believe that two key factors – one preprocedural and one postprocedural – may be central to translating these findings into clinical practice and defining priorities for future research:
- Patient selection (presence, nature, and severity of OAC intolerance or contraindications);
- The antithrombotic strategy adopted after LAAC.
Both warrant prospective investigation in dedicated randomized clinical trials.
The full manuscript is available in JAMA Cardiology
Congratulations to my co-authors, Claudio and Kamil, and special thanks to Prof. Capodanno for his mentorship.”
Title: Catheter-Based Left Atrial Appendage Closure vs Oral Anticoagulation in Patients With Atrial FibrillationA Systematic Review and Meta-Analysis
Authors: Claudio Laudani, Kamil Bujak, Daniele Giacoppo, Simone Finocchiaro, Luigi Cutore, Maria Sara Mauro, Pietro Redigolo, Placido Maria Mazzone, Giacinto Di Leo, Francesco Nasisi, Marco Spagnolo, Antonio Greco, Davide Capodanno
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