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Nicolas Gendron: From HIT to VITT
Oct 28, 2025, 07:00

Nicolas Gendron: From HIT to VITT

Nicolas Gendron, Research Fellow, Hematologist at Boston Children’s Hospital, shared a post on LinkedIn:

”From HIT to VITT-like syndromes: an overview of immune thrombocytopenias linked to anti-PF4 antibodies

Very pleased to announce the publication of our synthesis in La Revue du Praticien: “From heparin-induced thrombocytopenia to the emergence of immune thrombotic thrombocytopenia syndromes associated with anti-PF4 antibodies”

This work, carried out with Manon Jouffroy and David Smadja, traces the evolution of knowledge on thrombotic syndromes mediated by anti-PF4 antibodies, from HIT to the emergence of VITT (post-vaccine) and VITT-like (acute “infectious” or chronic, as we recently described in the NEJM Group).

We detail the pathophysiological, diagnostic and therapeutic aspects of these rare but important entities for the understanding of immunothrombosis mediated by anti-PF4 antibodies.”

Read the full article here.

Article: From heparin-induced thrombocytopenia to the emergence of immune thrombotic thrombocytopenia syndromes

Authors: Manon Jouffroy, David M. Smadja, Nicolas Gendron

Nicolas Gendron

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