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Owen McCarty: The Potential Benefit of Targeting FXI in Sepsis
Sep 26, 2025, 14:46

Owen McCarty: The Potential Benefit of Targeting FXI in Sepsis

Owen McCarty, Professor and Chair at Oregon Health and Science University, shared a post on LinkedIn:

“Our recent preclinical work highlighting the potential benefit of targeting FXI in sepsis. Led by Robert Silasi and Ravi Shankar Keshari, Ph.D with Aleksandr Shamanaev, Samantha (Sami) Moellmer, Cristina Puy Garcia, PhD, Joseph Shatzel, and Florea Lupu.”

Title: Protective effects of factor XI inhibition by abelacimab in a baboon model of live Staphylococcus aureus sepsis

Authors: Robert Silasi, Ravi S. Keshari, Tomohiro Abe, Stephanie D. Byrum, Girija Regmi, Cristina Lupu, Constantin Georgescu, Joe H. Simmons, Aleksandr Shamanaev, Samantha A. Moellmer, Cristina Puy, Joseph J. Shatzel, Dennis Province, Rick D. Edmondson, Samuel G. Mackintosh, Nathan L. Avaritt, Dan Bloomfield, David Gailani, Alan J. Tackett, Owen J.T. McCarty, Florea Lupu

Owen McCarty: The Potential Benefit of Targeting FXI in Sepsis

Read full artile here.

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