Sanjeev Bagai: How Platelet-Derived Serotonin Drives Lung Injury
Sanjeev Bagai, Chairman and Senior Consultant Paediatrician and Nephrologist at Nephron Clinic, shared a post on X about a recent article by Davide Marotta et al., published in Science Immunology, adding:
“Platelet-derived serotonin drives age-related lung pathology in SARSCoV-2: Platelets drive organ dysfunction in severe COVID19 thro distinct mechanisms – thromboinflammation in microvasculature.”
Among mediators released by activated platelets.”
Title: Platelet-derived serotonin drives age-related lung pathology in SARS-CoV-2 infection
Authors: Davide Marotta, Chiara Perucchini, Marta Grillo, Valeria Fumagalli, Pietro Di Lucia, Jordan Rixon, Micol Ravà, Leonardo Giustini, Chiara Malpighi, Giulia D’Uonnolo, Mariangela Scavone, Violette Mouro, Caitlin Abbott, Natalia Stachura-Chyla, Francesco Andreata, Erica Scalambrino, Marigrazia Clerici, Lorena Donnici, Marika Longo Minnolo, Donato Inverso, Raffaele De Francesco, Mauro Gaya, Zaverio M. Ruggeri, Armando Tripodi, Gian Marco Podda, Luca G. Guidotti, Matteo Iannacone, Marco De Giovanni
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