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SEC61B Mediated Platelet Hyperactivity in People with Diabetes
Aug 15, 2025, 23:35

SEC61B Mediated Platelet Hyperactivity in People with Diabetes

Eric Topol, physician-scientist, author of Super Agers and Ground Truths, spotlighted a compelling new study published in the Journal of Clinical Investigation (JCI), on X:

“Discovery of a mechanism for the increased risk of arterial blood clots in people with diabetes: platelet hyperactivity mediated by SEC61B, calcium balance inside these cells”

Read the full article here.

Article: SEC61B regulates calcium flux and platelet hyperreactivity in diabetes

Authors: Yvonne X. Kong, Rajan Rehan, Cesar L. Moreno,  Søren Madsen, Yunwei Zhang,  Huiwen Zhao,  Miao Qi  Callum B. Houlahan, Siân P. Cartland, Declan Robertshaw, Vincent Trang, Frederick Jun Liang Ong,  Michael Liu, Edward Cheng, Imala Alwis, Alexander Dupuy, Michelle Cielesh, Kristen C. Cooke, Meg Potter, Jacqueline Stöckli, Grant Morahan, Maggie L. Kalev-Zylinska, Matthew T. Rondina, Sol Schulman, Jean Y. H. Yang, G. Gregory Neely, Simone M. Schoenwaelder, Shaun P. Jackson, David E. James, Mary M. Kavurma, Samantha L. Hocking, Stephen M. Twigg, James C. Weaver, Mark Larance, Freda H. Passam

SEC61B Mediated Platelet Hyperactivity in People with Diabetes

 

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