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Sex-Specific Models for ASAH Show No Added Benefit over SMA2SH2ERS risk predictions
Jul 10, 2025, 18:16

Sex-Specific Models for ASAH Show No Added Benefit over SMA2SH2ERS risk predictions

International Journal of Stroke (IJS) recently shared a post on X:

”Study shows sex-specific models did not perform better than general SMA2SH2ERS risk prediction model.”

Read the full article here.

Following the development of the SMA2SH2ERS risk prediction model for aneurysmal subarachnoid hemorrhage (ASAH) in the general population, researchers explored ways to improve its accuracy.

To address known differences in ASAH incidence and predictor effects between men and women, they developed sex-specific models.

While these models included fewer variables and may offer greater usability, their predictive performance remained comparable to the original and similarly suboptimal.

None of the models demonstrated sufficient discriminatory power for clinical use.

Further validation is needed, along with future research into ethnicity-specific models that incorporate sex-based differences using an intersectional approach.

Sex-Specific Models for ASAH Show No Added Benefit over SMA2SH2ERS risk predictions

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