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Striking Stroke Science | HTRA1-AD-cSVD and CADASIL: Overlapping Features, Key Differences
Jul 6, 2025, 18:32

Striking Stroke Science | HTRA1-AD-cSVD and CADASIL: Overlapping Features, Key Differences

The International Journal of Stroke has recently shared an insightful post on X:

”Just Accepted!
New study shows HTRA1-AD-cSVD shares overlapping clinical and neuroimaging features with CADASIL

High prevalence of ICH in HTRA1-AD-cSVD.”

Read the full article here.

Stroke Science has leveled up, again!

This retrospective study, by Yi-Chung Lee et al., compares the clinical and neuroimaging characteristics of HTRA1-autosomal dominant cerebral small vessel disease (HTRA1-AD-cSVD) and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

While the two conditions share overlapping features, temporal pole involvement is more frequent in CADASIL.

Notably, the study highlights a previously under-recognized high prevalence of intracerebral hemorrhage (ICH) in HTRA1-AD-cSVD, suggesting the need for greater clinical awareness.

More scientific advancements and discoveries in the field of Stroke research featured in Hemostasis Today.