New Researchs at ACC26 on Everyday Clinical Decisions – The Lancet Group
The Lancet Group shared a post on LinkedIn:
“Cardiologists – The Lancet is at ACC26 with new research exploring everyday clinical decisions.
1.Aspirin vs clopidogrel after PCI:
Longest randomised follow-up (ten years) suggests sustained reductions in clinical events with clopidogrel compared with aspirin after PCI:
- Lower ischemic events with clopidogrel
- Lower bleeding events with clopidogrel
- No difference in mortality
‘These findings suggest that clopidogrel may be considered as the preferred agent for long-term antiplatelet monotherapy during the chronic maintenance phase after PCI’, say authors.
2.PCI before TAVI—necessary?
In patients with CAD, deferring PCI was noninferior to a PCI-first strategy at 1 year for death, MI, stroke, and major bleeding.
‘These findings support an initial conservative approach, although patient-tailored treatment strategies remain essential’, say authors.”
Title: Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: 10-year follow-up of the HOST-EXAM trial
Authors: Jeehoon Kang, Sungjoon Park, Han-Mo Yang, Eun-Seok Shin, Seung-Woon Rha, Jang-Whan Bae, Nam Ho Lee, Hyuck-Jun Yoon, Yoon Haeng Cho, Ung Kim, Song-Yi Kim, Sang-Hyun Kim, Jung-Kyu Han, Kyung Woo Park, Hyo-Soo Kim
Read the Full Article on The Lancet
Title: Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial
Authors: Ronak Delewi, Hugo M Aarts, Gijs M Broeze, Kimberley I Hemelrijk, Dirk Jan van Ginkel, Geert A A Versteeg, Maik J Grundeken, Bimmer E P M Claessen, Pim A L Tonino, Carl E Schotborgh, Martijn Meuwissen, Gert K van Houwelingen, Joanna J Wykrzykowska, Giovanni Amoroso, Tessel N Vossenberg, Pieter A Vriesendorp, Niels van Royen, Jurriën M ten Berg, Jan G P Tijssen, Michiel Voskuil
Read the Full Article on The Lancet
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