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New Researchs at ACC26 on Everyday Clinical Decisions – The Lancet Group
The Lancet
Mar 31, 2026, 13:49

New Researchs at ACC26 on Everyday Clinical Decisions – The Lancet Group

The Lancet Group shared a post on LinkedIn:

“Cardiologists – The Lancet is at ACC26 with new research exploring everyday clinical decisions.

1.Aspirin vs clopidogrel after PCI:

Longest randomised follow-up (ten years) suggests sustained reductions in clinical events with clopidogrel compared with aspirin after PCI:

  • Lower ischemic events with clopidogrel
  • Lower bleeding events with clopidogrel
  • No difference in mortality

‘These findings suggest that clopidogrel may be considered as the preferred agent for long-term antiplatelet monotherapy during the chronic maintenance phase after PCI’, say authors.

2.PCI before TAVI—necessary?

In patients with CAD, deferring PCI was noninferior to a PCI-first strategy at 1 year for death, MI, stroke, and major bleeding.

‘These findings support an initial conservative approach, although patient-tailored treatment strategies remain essential’, say authors.”

Title: Aspirin versus clopidogrel for chronic maintenance monotherapy after percutaneous coronary intervention: 10-year follow-up of the HOST-EXAM trial

Authors: Jeehoon Kang, Sungjoon Park, Han-Mo Yang, Eun-Seok Shin, Seung-Woon Rha, Jang-Whan Bae, Nam Ho Lee, Hyuck-Jun Yoon, Yoon Haeng Cho, Ung Kim, Song-Yi Kim, Sang-Hyun Kim, Jung-Kyu Han, Kyung Woo Park, Hyo-Soo Kim

Read the Full Article on The Lancet

The Lancet Group

Title: Deferral of percutaneous coronary intervention in patients undergoing transcatheter aortic valve implantation (PRO-TAVI): an investigator-initiated, multicentre, open-label, non-inferiority, randomised controlled trial

Authors: Ronak Delewi, Hugo M Aarts, Gijs M Broeze, Kimberley I Hemelrijk, Dirk Jan van Ginkel, Geert A A Versteeg, Maik J Grundeken, Bimmer E P M Claessen, Pim A L Tonino, Carl E Schotborgh, Martijn Meuwissen, Gert K van Houwelingen, Joanna J Wykrzykowska, Giovanni Amoroso, Tessel N Vossenberg, Pieter A Vriesendorp, Niels van Royen, Jurriën M ten Berg, Jan G P Tijssen, Michiel Voskuil

Read the Full Article on The Lancet

The Lancet Group

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ACC26 Bimmer E P M Claessen Carl E Schotborgh Dirk Jan van Ginkel Eun-Seok Shin Geert A A Versteeg Gert K van Houwelingen Gijs M Broeze Giovanni Amoroso Han-Mo Yang Health Hematology Hemostasis Hemostasis News Hemostasis Today Hugo M Aarts Hyo-Soo Kim Hyuck-Jun Yoon Jan G.P. Tijssen Jang-Whan Bae Jeehoon Kang Joanna J Wykrzykowska Jung-Kyu Han Jurriën M Ten Berg Kimberley I Hemelrijk Kyung Woo Park Maik J Grundeken Martijn Meuwissen Medicine Michiel Voskuil Nam Ho Lee Niels van Royen Pieter A Vriesendorp Pim A L Tonino Ronak Delewi Sang-Hyun Kim Seung-Woon Rha Song-Yi Kim Sungjoon Park Tessel N Vossenberg The Lancet The Lancet Group Ung Kim Yoon Haeng Cho
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