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Fibrinogen-Guided Management of Postpartum Hemorrhage – Transfusion Medicine KMC Manipal
Ganesh Mohan/LinkedIn
Mar 22, 2026, 16:03

Fibrinogen-Guided Management of Postpartum Hemorrhage – Transfusion Medicine KMC Manipal

Transfusion Medicine KMC Manipal shared a post on LinkedIn about a recent article by Ganesh Mohan et al, adding:

“Postpartum haemorrhage (PPH) continues to claim approximately 70,000 maternal lives annually, especially in resource-limited settings.

In this study, we explored how goal-directed bleeding management (GDBM) can transform outcomes by prioritizing fibrinogen correction.

This study reflects challenges unique to LMIC settings-delayed referrals, geographic barriers, and limited access to fibrinogen concentrates.

Key Findings:

  • Higher fibrinogen correction with GDBM (Increase of 74% vs 55%)
  • 43% reduction in cryoprecipitate turnaround time
  • Improved coagulopathy resolution (26.2% to 7.4%)”

Title: Early cryoprecipitate transfusion through goal-directed bleeding management in a real world setting – How important it is to focus on the fibrinogen in major obstetric Haemorrhage

Authors: Ganesh Mohan, Shamee Shastry, Prethika P. A., Deepika Chenna, Bemma Paonam

Read the Full Article on Transfusion Medicine

Fibrinogen-Guided Management of Postpartum Hemorrhage - Transfusion Medicine KMC Manipal

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Bemma Paonam bleeding disorders Deepika Chenna fibrinogen concentrates Ganesh Mohan GDBM Health Hematology Hemostasis Hemostasis News Hemostasis Today LMIC Medicine Postpartum Haemorrhage PPH Prethika P. A. Shamee Shastry Transfusion Medicine Transfusion Medicine KMC Manipal
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