Wael AlAnazi: Exceptional HLA-Matched Transplant Outcomes With Novel Thiotepa-Based Conditioning
Wael AlAnazi, Chairman and Hematology-Oncology Consultant at King Fahad Specialist Hospital Dammam, shared Syed Osman Ahmed‘s post on LinkedIn, adding:
“Impressive results!!!
I think this may be reference for sickle cell disease transplantation.
Do you have similar observations in Thalassemia?”
Syed Osman Ahmed, Consultant and Adult Hematologist at King Faisal Specialist Hospital and Research Centre, shared a post on LinkedIn about a recent article by Reem Alasbali et al. published in Bone Marrow Transplantation, adding:
“Outstanding outcomes in HLA-matched related donor transplant in adolescents and adults with sickle cell disease!
- 100% 2 year survival
- 0% Transplant related mortality
- 0% graft failure
- 0% Chronic Graft versus host disease
- Only 4% severe acute GVHD
Practice changing.
Congratulations to the authors of this collaborative work by Reem Alasbali et al led by Ali AlAhmari of King Faisal Specialist Hospital and Research Center and teams from Ministry of National Guard Health Affairs, Riyadh, Vanderbilt University Medical Center, Nashville and Imperial College London.”
Title: Excellent outcomes using a novel reduced intensity conditioning with thiotepa and post-transplant cyclophosphamide for HLA-matched related donor transplant in adolescents and adults with sickle cell disease
Authors: Reem Alasbali, Mohsen Alzahrani, Karina Wilkerson, Phavina Akhom, Fahad Alotaibi, Bader Alahmari, Josu de la Fuente, Michael R. DeBaun, Walid Rasheed, Hadeel Samarkandi, Riad El Fakih, Mostafa Saleh, Tusneem Elhassan, Hazza Alzahrani, Mahmoud Aljurf, Fahad Almohareb, Adetola A. Kassim, Ali AlAhmari
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 10, 2026, 07:41Adeeb Bazuhair: New Evidence for Catheter Directed Thrombolysis in Acute PE
-
Oct 10, 2026, 07:22Poppy Clarke: Turning Steps Into Support for Thrombosis Awareness
-
Oct 10, 2026, 07:12Hamzah Khan: The Role of Genuine Curiosity in Driving High-Impact Academic Research
-
Oct 10, 2026, 06:58Nita Radhakrishnan: Turning Evidence Into Action for Hemophilia Care in India
-
Oct 10, 2026, 06:48Nutan Kaushik: HemeNext 2.0 Brings Global Perspectives to Hematology
-
Oct 10, 2026, 06:43Suthesh Sivapalaratnam: Advancing Bleeding Disorder Care at EHC 2026
-
Oct 10, 2026, 02:38Brianne D.: Sex Differences in RIPK1 Signaling Following Intracerebral Hemorrhage
-
Oct 10, 2026, 02:17Dino Mehic: Managing Heavy Menstrual Bleeding in Patients with BDUC
-
Oct 10, 2026, 00:34Raphaëlle Dodart: Discussing the Mechanisms of Menstrual Hemostasis