Christoph B Olivier’s Team Explores Platelet Reactivity and Fibrin Clot-Strength in AF
Jan Hartmann, Chief Medical Officer at Haemonetics, reposted from Haemonetics on LinkedIn:
”Encouraging progress in personalized cardiovascular care.
A recent paper from Christoph B Olivier’s team at my alma mater, The University of Freiburg, explores “Platelet Reactivity and Fibrin Clot-Strength as assessed by TEG in Patients with Atrial Fibrillation undergoing Percutaneous Coronary Intervention”.
Their findings suggest that combined high platelet reactivity and increased platelet–fibrin clot strength after the PCI may elevate ischemic risk—though neither factor alone was predictive.
This aligns with data in broader post-PCI populations, with or without AFib:
- Young-Hoon Jeong, MD, PhD’s team (European Heart Journal, 2024) in South Korea showed that patients with combined platelet-fibrin clot strength and high platelet reactivity had the highest risk for MACE post-PCI (more than patients with either factor alone).
- A 2023 study from Fudan University in China reported similar results, where “a combination of high fibrinogen and HRPR may identify recurrent adverse ischemic events over 12 months.”
It’s encouraging to see continued momentum toward individualized post-intervention strategies, especially in tailoring OAC and antiplatelet therapy.
References:
Read the full article here.
Article: Platelet Reactivity and Fibrin Clot-Strength as assessed by TEG in Patients with Atrial Fibrillation undergoing Percutaneous Coronary Intervention
Authors: Diona Gjermeni, Hannah Vetter, Sofia Szabó, Viktoria Anfang, Carina Juelch, Stefan Leggewie, David Hesselbarth, Markus Jäckel, Daniel Duerschmied, Dietmar Trenk, Dirk Westermann, Christoph B Olivier
Stay updated on all scientific advances in the field of thrombosis with Hemostasis Today.
-
May 24, 2026, 17:48Flora Peyvandi: Crucial Role of Placental ADAMTS13 in Perinatal Survival
-
May 24, 2026, 17:13Mahtab Mashayekhi: The Evolving Role of Red Blood Cell Exchange in the Management of SCD
-
May 24, 2026, 17:12Silvina Graña: Helping Families Better Understand Hemophilia and Daily Life With Bleeding Disorders
-
May 24, 2026, 17:11Miikka Vikkula: Key Insights from the ISSVA 2026 World Congress
-
May 24, 2026, 17:10Mathieu Jackson: Proud to Be Present at This Historic Moment for the Global Bleeding Disorders Community
-
May 24, 2026, 17:09Ramina Fazeli: Highlighting the Emerging Role of Neutrophil Extracellular Traps in Ovarian Cancer
-
May 24, 2026, 16:12William Wallace: Normal B12 Levels May Still Cause Brain Damage and Cognitive Decline
-
May 24, 2026, 15:54Marc Carrier: Ottawa Race Weekend Raised Over 7,000 USD for Thrombosis Canada
-
May 24, 2026, 15:44Janak Sadhu: Building a Stroke-Free Mehsana Through Community Awareness and Healthcare Collaboration