Alfonso Rodriguez Espada: Data Suggests Thrombosis Is as Likely as Hereditary Angioedema in C1INH Deficiency
Alfonso Rodriguez Espada, Postdoctoral Fellow at BIDMC and Broad Institute of Harvard and MIT, shared on LinkedIn:
”Predicted loss of function SERPING1 variants are associated with reduced plasma C1-inhibitor and a polyphenotypic thrombotic disorder!
Data suggests thrombosis is as likely as hereditary angioedema in C1INH deficiency.”
Read the full article in Blood Advances.
Article: Population-scale Analysis Reveals Germline Loss of SERPING1 (C1-Inhibitor) is a Polyphenotypic Thrombotic Disorder
Authors: Alfonso Rodriguez Espada, Amelia Haj, Sean Joseph Jurgens, Harish Eswaran, Linda Sundler Björkman, Justine Ryu, Sharjeel Chaudhry, Satoshi Koyama, Xin Wang, Seung Hoan Choi, Simone Sanna-Cherchi, Aleena Banerji, Joel T Rämö, Patrick T. Ellinor, Steven P Grover Corresponding Author , Pavan K Bendapudi
Stay updated on all scientific advances in the field of thrombosis with Hemostasis Today.
-
Feb 23, 2026, 18:13Fight4Hematology Supports Research and Empowers the Next Generation – ASH
-
Feb 23, 2026, 17:59Wolfgang Miesbach: Real-World Evidence of Emicizumab on Joint Outcomes in Hemophilia A
-
Feb 23, 2026, 17:56Shiny K Kajal: The Transfusion Reaction We Often Miss
-
Feb 23, 2026, 17:53Radheshyam Meher: Contributing to the Transfusion Evidence Round-Up for International Childhood Cancer Day 2026
-
Feb 23, 2026, 17:46Mahesan Subramaniam: The Physiological Impact of Anger on Immunity
-
Feb 23, 2026, 17:42Bryan Fry: First Evidence That Bothrops atrox Venom Directly Activates Human Factor VII
-
Feb 23, 2026, 17:34Bastu Odoka: Why Blood Should NOT be Left at the Bedside to ‘Warm’
-
Feb 23, 2026, 17:28Henry Burkitt: Patients Are Challenging How the Medicines Policy System Works in England
-
Feb 23, 2026, 16:50Mutaz Al‑Sabah: Interesting Webinar on FH in Women is Now Available to Watch