When TACO Runs Hot: Rethinking Fever in Transfusion-Associated Circulatory Overload
Caitlin Raymond, Assistant Professor of Pathology and Transfusion Medicine at the University of Wisconsin-Madison, shared on LinkedIn:
”We’re taught that transfusion-associated circulatory overload (TACO) is purely hemodynamic – too much volume, too fast. But what if that’s only half the story?
Emerging data suggest that up to 40% of TACO cases involve fever, and not as a coincidence. These “hot-TACO” presentations hint at a proinflammatory component, challenging the traditional binary between “volume overload” and “immune reaction.”
In my latest post for Blood, Bytes, and Beyond, I explore:
– The evidence linking fever and inflammation to TACO
– How this blurs the line between TACO, TRALI, and sepsis
If you’ve ever struggled to distinguish these reactions at the bedside, or wondered why some TACO cases seem too intense for the volume given, this one’s for you.
Read the full piece here.”
Title: When TACO Runs Hot: Rethinking Fever in Transfusion-Associated Circulatory Overload
Author: Caitlin Raymond
Stay updated with Hemostasis Today.
-
Apr 12, 2026, 17:34Caitlin Raymond: Granulocyte Transfusions for the Overworked Fellow
-
Apr 12, 2026, 17:33Augustina Isioma Ikusemoro: ABO Typing Is Not the Same in Infants and Adults
-
Apr 12, 2026, 17:32Bastu Odoka: Same Blood Group Does Not Guarantee Compatibility
-
Apr 12, 2026, 17:31Jack Hadfield: SARS-CoV-2–Associated Lasting Mitochondrial Injury in Cardiomyocytes
-
Apr 12, 2026, 17:30Flora Peyvandi: ABB Milan Presentations During the ISTH 2026
-
Apr 12, 2026, 17:01Hafiz Saad Ullah: Introducing to Fully Automatic Peripheral Blood Smear Stainer
-
Apr 12, 2026, 16:53Najmul Hasan Forhad: A Simple Framework for Mastering Anticoagulant Therapy
-
Apr 12, 2026, 16:36Piotr Czempik: Patient Blood Management Means Safer Care, Better Quality, and Responsible Resource Use
-
Apr 12, 2026, 16:31Eishi Asano: Available Evidence and Unmet Needs in EEG Use During Stroke Management