Dr. Anok Singh Rana Answers: Why Did Miscarriage Happen Even After IVF?
Dr. Anok Singh Rana, Chief Operating Officer at Neelkanth ivf group, posted on LinkedIn:
“Why Can Miscarriage Still Happen After IVF?
An Honest Reality
IVF is an advanced medical science, but it is not a guarantee.
One of the most common and painful questions couples ask is:
‘Why did miscarriage happen even after IVF?’
The truth is, IVF reduces infertility challenges, but it does not completely eliminate the risk of miscarriage.
Average miscarriage risk after IVF:
- Around 10–20%,
- Varies based on age, embryo quality, and maternal health.
Common reasons for miscarriage after IVF:
- Embryo quality
Even after implantation, genetically abnormal embryos may not continue to develop. This remains the most common cause. - Age factor
After 35, egg quality declines, increasing the risk of chromosomal abnormalities. - Uterine factors
Fibroids, polyps, thin endometrium, or a mismatch in the implantation window can affect pregnancy continuation. - Hormonal imbalance
Low progesterone, thyroid disorders (T3/T4), uncontrolled diabetes, or PCOS can negatively impact early pregnancy. - Immunological and clotting disorders
Conditions like APS and thrombophilia can interfere with proper placental development. - Lifestyle and stress
Smoking, obesity, poor sleep, and chronic stress quietly reduce IVF success rates.
An important message for patients:
A miscarriage does not mean IVF has failed and it does not mean future pregnancy is impossible. Every miscarriage offers clinical insight to plan the next cycle in a more precise and personalized way.
From a clinician and healthcare leadership perspective:
Our responsibility is not only to achieve pregnancy,
but to ensure correct diagnosis, honest counseling, and emotional support.
IVF is science.
But a successful patient journey is built on trust, clarity, and care.”
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