Muhammad Ibrahim on Efficacy and Safety of Extended DOACs Use in VTE
Muhammad Ibrahim, Medical Researcher at Research Council of Pakistan, shared on LinkedIn:
”Excited to co-author this amazing systematic review and meta-analysis entitled: Efficacy and Safety of Direct Oral Anticoagulants for Extended Treatment of Venous Thromboembolism.
Clinical question: Should we continue DOACs long-term after initial VTE treatment?
Analysis of 5,600+ patients from RCTs showed:
83% reduction in VTE recurrence
62% reduction in all-cause mortality
No significant increase in major bleeding
Higher clinically relevant non-major bleeding
Bottom line: In properly selected, low-bleeding-risk patients, extended DOAC therapy provides a clear net clinical benefit for secondary prevention of VTE.
Special thanks to Saad Ahmed Waqas for giving me the opportunity to work on and help lead this project.
Read here.
Congratulations to the co-authors: Muhammad Waqas, Muhammad Ahmed, Maimoona Nasir, Muhammad Khalid Afridi, Gregg C. Fonarow.”
Article: Efficacy and Safety of Direct Oral Anticoagulants for Extended Treatment of Venous Thromboembolism: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Waqas Muhammad, Muhammad Ahmed, Muhammad Ibrahim, Maimoona Nasir, Muhammad Khalid Afridi, Gregg C. Fonarow, Saad Ahmed Waqas
Stay updated on all scientific advances with Hemostasis Today.
-
Apr 30, 2026, 18:19Deva Nanda TK: A Practical Overview of Dural Sinuses and The Venous Drainage of the Brain
-
Apr 30, 2026, 18:08Amrit Kaur Kaler: The Hidden Genetic Drivers of Thrombosis
-
Apr 30, 2026, 18:06Alejandro González Veliz: The Most Dangerous Mistake After Getting a Stent
-
Apr 30, 2026, 18:03Carmen Ruiz: First Arterial Mechanical Thrombectomy in New Zealand Using the ARTIX System
-
Apr 30, 2026, 17:52Simon Senanu: von Willebrand Disease May Be Missed Despite Normal Tests
-
Apr 30, 2026, 17:20José Antonio García Erce: Why Healthy Older Adults Should Keep Donating Blood?
-
Apr 30, 2026, 17:13Paul Logan: Decoding the Words ‘He’s on blood thinners’
-
Apr 30, 2026, 17:01Jason Andrade: A Decade-Long Quest Proves Early Ablation Halves Persistent AF Burden
-
Apr 30, 2026, 16:56Oliver Maracic: Could Co-Targeting ALK with FAK/PYK2 Help Mitigate the High VTE Burden Seen in ALK with NSCLC