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Christian Heiss: A Practical Synthesis on Peripheral Artery Disease in the Legs
Christian Heiss/LinkedIn
Feb 4, 2026, 17:04

Christian Heiss: A Practical Synthesis on Peripheral Artery Disease in the Legs

Christian Heiss, Associate Head of Medical School (Research and Innovation) at the University of Surrey, Professor and NHS Consultant in Interventional Cardiovascular Medicine, shared a post on LinkedIn:

”New NEJM Clinical Practice review on PAD in the legs (McDermott).

A really practical synthesis that reinforces a few key points:

  • PAD remains common and functionally limiting, with diagnosis still anchored around ABI <0.90. My take: Using quantitative Doppler waveform analysis.
  • Event prevention is ‘full-spectrum’: intensive lipid-lowering (statins), antiplatelet therapy / low-dose aspirin + rivaroxaban (where appropriate), BP <130/80, and in relevant patients GLP-1RA (semaglutide) and SGLT2 inhibitors.
  • For symptoms, supervised or structured home-based walking exercise remains foundational; revascularisation is best reserved for persistent symptoms not responding to exercise.
  • Worth a read for anyone building PAD pathways across primary care/CDC and vascular services.”

Title: Peripheral Artery Disease in the Legs

Author: Mary M. McDermott

Read the Full Article on NEJM Clinical Practice 

Christian Heiss: A Practical Synthesis on Peripheral Artery Disease in the Legs

Title: Prognostic and predictive value of ultrasound-based estimated ankle brachial pressure index at early follow-up after endovascular revascularization of chronic limb-threatening ischaemia: a prospective, single-centre, service evaluation

Authors: Alexander D Rodway, Lydia Hanna, Jenny Harris, Rachael Jarrett, Charlotte Allan, Felipe Pazos Casal, Benjamin C T Field, Martin B Whyte, Nikolaos Ntagiantas, Ivan Walton, Ajay Pankhania, Simon S Skene, Gary D Maytham, Christian Heiss

Read the Full Article on eClinicalMedicine

Christian Heiss

 

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Ajay Pankhania Alexander D Rodway Ankle Brachial Pressure Index Benjamin C T Field Charlotte Allan Christian Heiss eClinicalMedicine eClinicalMedicine – The Lancet Discovery Science Endovascular Revascularization Felipe Pazos Casal Gary D Maytham Health Hematology Hemostasis Hemostasis Today Ivan Walton Jenny Harris Lydia Hanna Martin B Whyte Medicine NEJM New England Journal of Medicine Nikolaos Ntagiantas nterventional Cardiovascular Medicine PAD Peripheral Artery Disease Rachael Jarrett Simon S Skene The Lancet Discovery Science thrombosis University of Surrey
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