ICAS Not a Factor: Post-EVT Intensive BP Control within 24 hrs Worsens Outcomes
International Journal of Stroke (IJS) shared a reminder post on X:
”Intensive blood pressure lowering in acute stroke with intracranial stenosis post-thrombectomy: A secondary analysis of the OPTIMAL-BP trial.”
Read the article here.
IJS is here to remind us about the important from a ‘Intensive blood pressure lowering in acute stroke with intracranial stenosis post-thrombectomy: A secondary analysis of the OPTIMAL-BP trial‘ by Kwang Hyun Kim et al.
Asian randomized trials indicate that intensive blood pressure (BP) control within 24 hours after successful endovascular thrombectomy (EVT) is associated with poorer functional outcomes compared to conventional BP management.
Despite the high prevalence of intracranial atherosclerotic stenosis (ICAS) in this population, ICAS did not significantly modify the effect of intensive BP lowering.
These findings suggest that intensive BP management should be avoided post-EVT regardless of ICAS status to optimize recovery.

Hemostasis Today, your daily update on stroke management.
-
Apr 11, 2026, 13:51David McIntosh: Vital Plasma Derived Medicines – The Anomalous UK Scene
-
Apr 11, 2026, 13:47Samrawit Terefe: O Negative Blood Is the Universal Donor With Extreme Scarcity
-
Apr 11, 2026, 13:39Dheeraj Garg: Rethinking Cardiovascular Disease – A Cardiologist’s Perspective
-
Apr 11, 2026, 13:37Kushal Bhatia: Is The 4.5-Hour Thrombolysis Window Officially Outdated?
-
Apr 11, 2026, 13:35William Aird: Why Did Mammalian Red Blood Cells Give Up Their Nucleus?
-
Apr 11, 2026, 13:30Ken Kuang: Gravity Is Constant, But Your Vein Health Doesn’t Have to Be
-
Apr 11, 2026, 13:21Mascha Kern: Measuring Gender’s Role in Stroke and Migraine
-
Apr 11, 2026, 13:10Danique Steeghs: Key Findings from a Microfluidic Chemiluminescent Thrombin Generation Assay
-
Apr 11, 2026, 13:06Shanvi Mahi: A Validated Tool to Explore Lived Experiences After Stroke Rehabilitation