Søren Hough: A Bispecific siRNA Design for Simultaneous Gene Silencing in Cancer
Søren Hough, Editor, Drug Modalities and TIDES Global at BioXconomy, shared a post on LinkedIn:
“Genetics is a lot more complicated than ‘turn off Gene A, get Disease B.’
Oftentimes, genetic networks look more like logic puzzles, requiring a sometimes dizzying combination of activation, silencing, modulating, and other tweaks to achieve a particular outcome.
That’s the logic researchers in Osaka, Japan, have applied to their ‘bispecific’ siRNA design: a single molecule that can shut off two genes at once. Their goal is to tackle diseases like cancer by finding consensus regions between genes with the goal of simultaneous gene silencing. Doing so could help bypass genetic redundancies that make some cancer types resistant to treatment.
Check out my story over at BioXconomy .”
Stay updated with Hemostasis Today.
-
Aug 26, 2026, 18:38Maia Meier: Muhiba’s Story of Courage, Resilience and Hope With Type 3 VWD
-
Aug 26, 2026, 18:27Isabella Presch: Not Every Genome-Editing Program Needs to Start From Zero
-
Aug 26, 2026, 18:24New Educational Content for the Bleeding Disorders Community – EAHAD
-
Aug 26, 2026, 18:14N. Mariana S. Vasquez: From Skin and Gut to Celiac Disease
-
Aug 26, 2026, 18:13Francesca Granata: What Happens When Patients Become Researchers and Researchers Become Advocates?
-
Aug 26, 2026, 18:11Maxima Mendez: Statins Are No Longer the Whole Story
-
Aug 26, 2026, 18:06Ashkan Shoamanesh: ANNEXa-I Analyses Inform Individualized Treatment in Intracranial Hemorrhage
-
Aug 26, 2026, 18:01Sam Tsimikas: Lp(a) and Oxidized Phospholipids Reveal a New Link Between Hypercoagulability and Stronger Clot Formation
-
Aug 26, 2026, 17:52Kamlesh Darji: A Practical Guide to Interpreting Coagulation Tests