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Is It Safe to Briefly Stop Anticoagulation After VTE? – RPTH Journal
RPTH Journal
Feb 24, 2026, 16:01

Is It Safe to Briefly Stop Anticoagulation After VTE? – RPTH Journal

RPTH Journal shared a post on LinkedIn about a recent article by Lisbeth Eischer et al, adding:

“Is it safe to briefly stop anticoagulation after VTE?

After at least 3 months of anticoagulation for VTE, some strategies recommend off-therapy D-dimer testing to assess recurrence risk, but how safe is temporary discontinuation?

Key takeaways from this systematic review and meta-analysis:

  • Early VTE recurrence within 30 days occurred in 1.04% of patients
  • No fatal recurrences were reported
  • Unprovoked VTE was associated with a higher early recurrence risk
  • Brief interruption of anticoagulation for risk assessment appears safe.”

Title: The incidence of early recurrent venous thromboembolism: a systematic review and meta-analysis

Authors: Lisbeth Eischer, Paul A. Kyrle, Alexandra Kaider, Anton Schmidt, Brigitte Wildner, Anja Boc, Charlotte Bradbury, Anetta Undas, Francis Couturaud, Matteo Nicola Dario Di Minno, Geert-Jan Geersing, David Jimenez, Sameer Parpia, Gualtiero Palareti, Daniela Poli, Daniel P. Potaczek, Paolo Prandoni, Sam Schulman, Astrid van Hylckama Vlieg, Michal Zabczyk, Sabine Eichinger

Read the Full Article on RPTH Journal

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Alexandra Kaider Anetta Undas Anja Boc Anticoagulation Anton Schmidt Astrid van Hylckama Vlieg Brigitte Wildner Charlotte Bradbury D dimer Daniel P. Potaczek Daniela Poli David Jimenez Francis Couturaud Geert-Jan Geersing Gualtiero Palareti Health Hemostasis Today Lisbeth Eischer Matteo Nicola Dario Di Minno Medicine Michal Zabczyk Paolo Prandoni Paul A. Kyrle Sabine Eichinger Sam Schulman Sameer Parpia thrombosis VTE
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