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Alfonso Tafur: Different Cancer Sites Drive Different Thrombotic Phenotypes
Mar 9, 2026, 15:30

Alfonso Tafur: Different Cancer Sites Drive Different Thrombotic Phenotypes

Alfonso Tafur, Vascular Medicine Fellowship Program Director at University of Chicago, Director of Vascular Medicine Department at NorthShore University, shared on LinkedIn:

”For years, many of us have treated cancer-associated thrombosis as if it were a single disease.

The data keep reminding us: it isn’t.

In the RIETE Registry, we looked at 18,000+ cancer patients vs. 88,000 without.

Within 90 days — 2.5× higher recurrent VTE, ~40% higher major bleeding.

But the real signal? Cancer site matters.

Lung and pancreatic drive clot risk. GI and GU drive bleeding risk.

Cancer-associated thrombosis is not one disease.

It is many biologically different thrombotic phenotypes.

Proud to be part of this team working toward precision vascular care.”

Proceed to the video attached to the post.

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