Wolfgang Miesbach Announces the New English Edition of “Gene Therapy Concepts in the Treatment of Haemophilia”
Wolfgang Miesbach, Professor of Medicine at Frankfurt University Hospital, shared a post on LinkedIn:
”I’m delighted to announce the newly published English edition of our book: ‘Gene Therapy Concepts in the Treatment of Haemophilia’.
After decades of research, gene therapies for Haemophilia A and B are now a reality – with the potential to sustainably improve patients’ quality of life and speak of phenotypic cure for the first time.
The book provides up-to-date information on:
- Basics of Haemophilia
From pathophysiology to therapy with clotting factors and subcutaneous agents.
- Gene Therapy Approaches and Current Study Results
AAV, Lentivirus, Gene Editing, and other therapeutic concepts.
- Patient Selection and Individual Therapy
Criteria for selecting suitable patients.
- Immunology
Immune responses to AAV-mediated gene therapy, immunohematology, challenges with antibodies and immune reactions.
- Laboratory and Diagnostics
Monitoring clotting factor levels, lab diagnostics, quality control, and new lab methods.
- Liver-Related Issues
Impacts of gene therapy on the liver and its function.
- Interdisciplinary Collaboration
Necessity and benefits of the “Hub and Spoke” model for care.
- Future Perspectives and Innovation
Opportunities, challenges, and outlook on personalized medicine and innovative therapies.
- Shared Decision Making
Active involvement of patients and treaters in therapy decisions, especially for gene therapy selection and education.
A clear recommendation for everyone interested in innovative therapies, translating research into the clinic, and the future of personalized medicine.”
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