ABO-Incompatible Transfusions and Severe Allergic Reactions – ISBT
International Society of Blood Transfusion (ISBT) shared a post on LinkedIn about a recent article by Lucile Malard et al. published in Vox Sanguinis:
“Recently published in Vox Sanguinis
Association between group B major ABO-incompatible platelet or plasma transfusion and severe allergic reactions: A nationwide haemovigilance analysis suggesting a role for α-gal syndrome.
Key takeaways:
- Transfusing group B or AB platelets/plasma to group O recipients in France is linked to higher risk of severe allergic transfusion reactions (ATR).
- The risk is stronger with platelet transfusions than plasma, possibly related to α-gal syndrome.
- Recommendation: Group O recipients should receive ABO-identical platelets or plasma whenever possible.
A step forward in safer, personalized transfusion care.”
Title: Association between group B major ABO-incompatible platelet or plasma transfusion and severe allergic reactions: A nationwide haemovigilance analysis suggesting a role for α-gal syndrome. A Biomedical Excellence for Safer Transfusion Collaborative study
Authors: Lucile Malard, Cléo Beuscart, Luc de Chaisemartin, Virginie de La Taille, Catherine Humbrecht, Syria Laperche, Pierre Tiberghien
Read the Full Article on Vox Sanguinus Journal
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