Blood Journals Portfolio/X
Jul 28, 2025, 12:04
ChAdOx1 and Shear‑Dependent Platelet Aggregation: Uncovering a New Thrombotic Pathway
The Blood Journals Portfolio reported on its official X:
“ChAdOx1 induces platelet aggregation under shear via biomechanically activated integrin αIIbβ3, bypassing GPIb-dependent platelet adhesion pathway.”
Title: Shear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosis
Authors: Yiyao Catherine Chen, Naveen Eugene Louis Richard Louis, Angela Huang, Allan Sun, Alexander Dupuy, Laura Moldovan, Tiana Pelaia, Jianfang Ren, Taylor S. Cohen, Sarah C. Gilbert, Huyen Tran, Karlheinz Peter, James D. McFadyen, Lining Arnold Ju
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Aggregation
Alexander Dupuy
Allan Sun
Angela Huang
ASH
ASH Publications
Blood Journals Portfolio
Health
Hematology
Hemostasis Today
Huyen Tran
James D. McFadyen
Jianfang Ren
Karlheinz Peter
Laura Moldovan
Lining Arnold Ju
Medicine
Naveen Eugene Louis Richard Louis
Platelet
Sarah C. Gilbert
Taylor S. Cohen
Thrombotic Pathway
Tiana Pelaia
Yiyao Catherine Chen
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