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Marcin Czerwinski: Neutralizing Anti-AAV Antibodies in Hemophilia B Gene Therapy
Mar 28, 2026, 17:01

Marcin Czerwinski: Neutralizing Anti-AAV Antibodies in Hemophilia B Gene Therapy

Marcin Czerwinski, Professor at Hirszfeld Institute of Immunology and Experimental Therapy, shared a post on LinkedIn about a recent article by Radoslaw Kaczmarek, adding:

“Radoslaw (Radek) Kaczmarek just wrote a great commentary about neutralizing anti-AAV antibodies (NAbs) in hemophilia B therapy that can block transduction, thereby abolishing efficacy.

It seems that this is not the case…”

Title: Hemophilia B gene therapy: a NAb-solute barrier overcome by AAV5

Author: Radoslaw Kaczmarek

Read the Full Article on RPTH Journal

Marcin Czerwinski: Neutralizing Anti-AAV Antibodies in Hemophilia B Gene Therapy

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