Piotr Czempik: Hidden Platelet Dysfunction in Sepsis and Septic Shock
Piotr Czempik, Chair of Department of Anesthesiology and Intensive Care at Medical University of Silesia, shared on LinkedIn about his recent article published in Hemato, adding:
”Proud to share the latest publication: ‘Platelet Function and Morphology in Patients with Sepsis and Septic Shock: A Retrospective Pilot Study’.
Sepsis remains one of the most challenging conditions in intensive care medicine.
While thrombocytopenia is a well‑known prognostic marker, this study explores a deeper question:
Can platelet function and morphology provide additional insight into sepsis severity?
Key findings:
- Platelet aggregation was impaired across multiple assays despite normal platelet counts and morphology.
- ROTEM‑derived platelet contribution to clot strength remained within normal limits.
- No association was found between platelet function/morphology and ICU mortality.
- An inverse correlation emerged between ROTEM platelet contribution and SOFA score – suggesting a potential link to sepsis severity.
Takeaway:
Functional platelet deficits may occur even when structural parameters appear normal.
This opens the door to refining how we assess coagulation and inflammation in septic patients.”
Title: Platelet Function and Morphology in Patients with Sepsis and Septic Shock: A Retrospective Pilot Study
Author: Piotr Czempik
Stay updated on all scientific advances with Hemostasis Today.
-
Apr 21, 2026, 16:04Akshat Jain: Personalized Hemophilia Care in the Era of Novel Therapies
-
Apr 21, 2026, 16:03Abdelaziz Fahem։ Novo Nordisk Reports Positive Phase 3 Results for Etavopivat
-
Apr 21, 2026, 16:01Augustina Isioma Ikusemoro: ABO Discrepancies in Transfusion Practice
-
Apr 21, 2026, 15:56Haroon A Mann: Focusing on Inequities in Haemophilia Care in Low-Resource Settings at WHC 2026
-
Apr 21, 2026, 15:56Mohammed Murad Hossain: Final Presentation and Certificate Award Ceremony
-
Apr 21, 2026, 15:51Chokri Ben Lamine: High-Yield Differentiation of Eosinophilic Disorders
-
Apr 21, 2026, 15:48David Palma: From Clinical Trials to your Clinic in IJROBP The Red Journal
-
Apr 21, 2026, 15:46William Wallace: Hidden Vitamin B12 Deficiency and Better Testing Methods
-
Apr 21, 2026, 15:36Tagreed Alkaltham։ Reaching Blood Donors and Inspiring Them to Give Blood