Stuart T. Haines: Pharmacist-Led Warfarin Management Improves Therapeutic Control in HeartMate 3 LVAD Patients
Stuart T. Haines, Editor-in-Chief JACCP, Professor and Director of Professional Development at University of Mississippi School of Pharmacy, shared on LinkedIn about a recent article by Bailey M. Colvin et al, published in Journal of the American College of Clinical Pharmacy, adding:
”The evidence for pharmacist-managed anticoagulation in patients just got a lot stronger.
A new study published in the Journal of the American College of Clinical Pharmacy – the largest multicenter cohort focused exclusively on LVAD patients – found that pharmacist-led warfarin management achieved a mean time-in-therapeutic range (TTR) of 65.6% versus 45.8% in patients managed by nonpharmacist clinicians.
That near-20-point advantage held after multivariable adjustment and came with no significant increase in clinically significant bleeding.
This fills a real evidence gap.
Prior studies in LVAD populations were small, single-center, and often included older device generations.
This study’s multicenter design and exclusive focus on the HeartMate 3 LVAD reflect current clinical practice – and the results strongly support the key role that pharmacists can play in the care of this very complex patient population under collaborative practice agreements.
Congratulations to authors Bailey Colvin, PharmD, BCCP, Lauren Kunkel, PharmD, BCCP, and the entire investigative team for this important contribution to the literature!”
Title: Comparing Pharmacist-Managed Warfarin Versus Usual Care in HeartMate 3 Patients: A Multicenter Retrospective Observational Study
Authors: Bailey M. Colvin, Lauren Kunkel, Abby Bauer, April S. Britt, Christine Cadiz, Paige Carrigan, Teresa Chu, Kathleen Faulkenberg, Corinn Floyd, Ian Hollis, Mackenzie Payne, Amanda Prosenjak, Sijin Wen, Jordan C. Wilkie, Meiling Zheng, Kazuhiko Kido
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