Katie Baca-Motes: What Can Menstrual Cycle Physiology Tell Us About Health Beyond Reproduction?
Katie Baca-Motes, CEO and Co-Founder of GSD Health Research, Co-Founder and Advisor at Scripps Research Digital Trial Center, shared a post on LinkedIn about a recent article by Marie Gombert-Labedens et al., published in Science Advances Journal, adding:
”What can menstrual cycle physiology tell us about health beyond reproduction?
A new paper in Science Advances by Marie Gombert Labedens, Alan Taitz, Orsolya Kiss, and Fiona Baker explores this question through an open-source framework called WAVES (Women’s Health Assessment through Variability in Endocrine-related Signals).
The authors applied WAVES to basal body temperature data from 5,674 menstrual cycles across 753 participants aged 18-42 years. The framework extracts 32 menstrual cycle metrics across temperature level, timing, variability, and cycle shape.
Using temperature data, the authors found measurable age-related differences, including higher average temperatures, shorter cycles driven largely by a shorter follicular phase, and greater cycle-to-cycle variability.
They also found that several temperature-related metrics showed moderate to strong within-person stability across cycles. In other words, some menstrual temperature patterns appear to reflect individual-specific physiological footprints over time.
As more physiological data are collected through wearables and other digital tools, frameworks like WAVES could help researchers ask better questions about menstrual signals, aging, individualized physiology, and digital biomarkers.
Many thanks to the authors for making both the framework and methodology openly available to the research community.”
Title: Identifying menstrual metrics as personal health markers: Age trends and individual footprints in temperature across 5674 cycles
Authors: Marie Gombert-Labedens, Alan Taitz, Orsolya Kiss, Fiona C. Baker
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