Alireza Fatemi: TNF-α as a Biomarker in Atrial Fibrillation
Alireza Fatemi, BMC Journals Reviewer at BMC, shared on LinkedIn about a recent article he and his colleagues co-authored, published in Clinical and Applied Thrombosis/Hemostasis, adding:
”I’m pleased to share our recent publication in Clinical and Applied Thrombosis/Hemostasis (Impact Factor: 2.3, Q2, 2026):
‘Association Between TNF-Alpha Levels and Atrial Fibrillation Outcomes: A Systematic Review and Meta-Analysis.’
In this comprehensive systematic review and meta-analysis, we synthesized evidence from 23 studies comprising 2,369 atrial fibrillation patients and 6,091 controls.
Our pooled analysis revealed that elevated TNF-α levels are significantly associated with the presence of atrial fibrillation (SMD = 1.15; P = 0.0001).
However, we observed substantial heterogeneity across studies, highlighting the need for standardized methodologies in future research.
These findings reinforce the role of inflammation in AF pathogenesis and suggest TNF-α as a potential biomarker for risk stratification.
Special thanks to my co-authors, Bahar Amirgholami, Yasmin Yazdooei, Aylin Taghipour, Amirali Zamani, and Ali Ajdarkosh.”
Title: Association Between TNF-Alpha Levels and Atrial Fibrillation Outcomes: A Systematic Review and Meta-Analysis
Authors: Alireza Fatemi, Bahar Amirgholami, Yasmin Yazdooei, Aylin Taghipour, Amirali Zamani, Ali Ajdarkosh
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