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Eltrombopag with Immunosuppressive Therapy Shows Promising Safety in Pediatric Severe Aplastic Anemia – Phase 2 ESCALATE Trial Results
Sep 2, 2025, 08:43

Eltrombopag with Immunosuppressive Therapy Shows Promising Safety in Pediatric Severe Aplastic Anemia – Phase 2 ESCALATE Trial Results

Blood Journals Portfolio shared a post on X:

“Eltrombopag’s pharmacokinetics profile was similar to that seen in patients with immune thrombocytopenia, with no unexpected safety signals.”

Title: Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: phase 2 ESCALATE trial

Authors: Akiko Shimamura, Alexey Maschan, Carolyn Bennett, Sujith Samarasinghe, Jason E. Farrar, Chi-kong Li, Nongnuch Sirachainan, Bunchoo Pongtanakul, Patcharee Komvilaisak, Ludmila Zubarovskaya, Jennifer A. Rothman, Kelly Walkovich, Taizo A. Nakano, Alison A. Bertuch, Anabela Ferrao, Rukhmi Bhat, Rabi Hanna, Kathleen Overholt, Jessica Boklan, Tze Fang Wong, Qinxia Wang, Patrick Urban, Brigitte Strahm, Winfred Wang, Adrianna Vlachos, David A. Williams

Eltrombopag

Eltrombopag

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Adrianna Vlachos Akiko Shimamura Alexey Maschan Alison A. Bertuch Anabela Ferrao Brigitte Strahm Bunchoo Pongtanakul Carolyn Bennett Chi-kong Li David A. Williams Jason E. Farrar Jennifer A. Rothman Jessica Boklan Kathleen Overholt Kelly Walkovich Ludmila Zubarovskaya Nongnuch Sirachainan Patcharee Komvilaisak Patrick Urban Qinxia Wang Rabi Hanna Rukhmi Bhat Sujith Samarasinghe Taizo A. Nakano Tze Fang Wong Winfred Wang
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