Federica Sepe: Are Biomarkers Finally Ready for Precision Stroke Medicine?
Federica Sepe, Neurologist at Bufalini Hospital, shared a post on LinkedIn about a recent article by Steffen Tiedt et al., published in The Lancet Neurology, adding:
“Are biomarkers finally ready for precision stroke medicine?
A new Lancet Neurology consensus review provides one of the most comprehensive roadmaps for translating stroke biomarkers into clinical practice. Rather than proposing another list of promising candidates, the authors define 17 research priorities and 5 minimum reporting datasets to improve standardization and accelerate clinical implementation.
Three key take-home messages:
- Blood, CSF and imaging biomarkers should be integrated rather than evaluated in isolation.
- Standardized reporting is essential to move from discovery to clinical adoption.
- Future precision stroke care will likely rely on multimodal models combining clinical variables, neuroimaging, AI and biomarkers.
My perspective
The next challenge is no longer identifying new biomarkers, but determining which combinations of biomarkers provide actionable clinical information for diagnosis, prognosis and treatment selection. Integrating artificial intelligence with multimoda.”
Title: Biomarkers for advancing diagnosis and prognosis in stroke
Authors: Steffen Tiedt, Alejandro Bustamante, Alan Cameron, Pol Camps-Renom, Gerrit M. Grosse, Johanna Ospel, Bastian Volbers, Heinrich J. Audebert, Julia Aulin, Bastian Cheng, Charlotte Cordonnier, Jonathan M. Coutinho, Ana Catarina Fonseca, Michael D. Hill, Märit Jensen, Christina Jern, Joseph Kamtchum-Tatuene, Mira Katan, Peter J. Kelly, Anna Kopczak, Robin Lemmens, Arne G. Lindgren, James J. M. Loan, Christian H. Nolte, Laurent Puy, Luca Saba, Rustam Al-Shahi Salman, Else Charlotte Sandset, Magdy H. Selim, Pierre Seners, Nikola Sprigg, Hsin-Hsi Tsai, Karen M. Doyle, Joan Montaner, Floris H. B. M. Schreuder, Luciano Sposato, Neshika Samarasekera, John J. McCabe
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