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Boby Varkey Maramattom: Thrombolysis in Acute Ischemic Stroke With an Unruptured Aneurysm
Aug 18, 2026, 19:37

Boby Varkey Maramattom: Thrombolysis in Acute Ischemic Stroke With an Unruptured Aneurysm

Boby Varkey Maramattom, Consultant Neurologist and Interventional Neurologist at Lourdes Hospital, Kochi Apollo Hospital, Angamaly Ajantha Clinic, shared a post on X about a recent article by Rongzhi Lun et al., published in The Neurohospitalist, adding:

“An acute ischemic stroke in a patient who is found to have an unruptured aneurysm.

Do you thrombolyse or not?

We just had a young man of 26 with an internal capsular infarct and a large ICA bifurcation partially thrombosed aneurysm on the same side.

Incidental unruptured intracranial aneurysms are found in 3.6%–6.6% of patients with ischemic stroke.

However, aneurysms rarely cause acute ischemic stroke; either through aneurysm thrombosis with distal embolization, thrombus extending into the parent artery, or arterial compression.

AHA guidance supports IV thrombolysis for aneurysms less than 10 mm, Data on thrombectomy in thrombosed aneurysm-related stroke remain sparse.

Aneurysms involving the occluded parent artery may carry greater post-IV thrombolysis rupture risk.”

Title: Thrombolysis in Acute Stroke Due to Thrombosed Aneurysm

Authors: Rongzhi (Ronda) Lun, Elana Adela Cora, Dana Iancu, Justin Graveline, Priya Figurado, Michel Shamy

Boby Varkey Maramattom

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