Adam Urato: How SSRIs May Affect Maternal and Fetal Serotonin
Adam Urato, Maternal-Fetal Medicine Physician at MetroWest Medical Center, shared a post on X about a recent article by Amy L. Salisbury et al., published in Neuropsychopharmacology, adding:
“SSRIs have profound chemical impact on the pregnant mom and her baby.
This study showed an EIGHT-fold reduction in mom’s platelet serotonin, and FOUR-fold decrease in baby’s.
Lower serotonin levels were associated with more abnormal (fidgety/restless) fetal movements on ultrasound.”
Title: Fetal behavior and gestational serotonin reuptake inhibitor exposure: relationships between behavior, drug dosage, plasma drug level, and a measure of drug bioeffect
Authors: Amy L. Salisbury, George M. Anderson, Amy Yang, Catherine S. Stika, Laura J. Rasmussen-Torvik, Jacqueline K. Gollan, Katherine L. Wisner
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