Vipin M. Vashishtha: Mild COVID-19 and Malaria Leave Measurable Fingerprints on the Clotting System
Vipin M. Vashishtha, Past Covener, ACVIP IAP at Indian Academy of Pediatrics, shared a post on X about a recent article by Erens Spiff Ekprikpo et al., published in PLOS Global Public Health, adding:
“Even mild infections can leave measurable fingerprints on the blood-clotting system.
A case-control study of 220 adults in Nigeria compared mild COVID-19, malaria, co-infection and healthy controls.
All three infected groups showed increased platelet-size variability, while D-dimer levels were highest in people with both infections. Clotting-related markers also showed sex-specific differences.
Two very different pathogens — a virus and a parasite — can disturb the body’s clotting balance, and when they strike together, the effects on clot formation and breakdown may be greater.
Why it matters: In malaria-endemic regions, even apparently mild infections may alter haemostasis. However, this small observational study measured biomarkers—not clinical clotting events—so it does not establish that these changes cause thrombosis.”
Title: Sex-specific hemostatic responses and alterations of Platelet Distribution Width (PDW) and D-dimer in mild COVID-19, Malaria, and co-infection in a tropical setting: A case-control study in Port Harcourt, Nigeria
Authors: Erens Spiff Ekprikpo, Stella Urekweru Ken-Ezihuo, Zaccheaus Awortu Jeremiah
Stay updated with Hemostasis Today.
-
Oct 11, 2026, 21:22Shayan Roshan: Happy to Share Two Research Milestones in Trauma Care and Pancreatic Cancer
-
Oct 11, 2026, 21:16Chokri Ben Lamine: Anemia in Myelofibrosis – Multiple Mechanisms, Limited Responses
-
Oct 11, 2026, 21:03Carmela Walker: Supporting Warriors Living With SCD Through Dental Care and Advocacy
-
Oct 11, 2026, 21:00Rishdha Roshad: Intraoperative Cell Salvage – Turning Blood Loss into an Opportunity for Recovery
-
Oct 11, 2026, 20:59Anthony R. Sloan: Honored to Share Our Work at the 20th Midwest Platelet Conference
-
Oct 11, 2026, 16:57Shiny K. Kajal: Japan Advances Artificial Blood via Haemoglobin Vesicles Trials
-
Oct 11, 2026, 16:45Luca Scarcia: Rescue Stenting Superior When Posterior Circulation Thrombectomy Fails
-
Oct 11, 2026, 16:27Giuseppe Bellelli: Reevaluating Anticoagulation Net Benefit in Frail Older Adults
-
Oct 11, 2026, 16:17Johnathan Whetstine: How Does MYC Go From 2 Copies to an Amplified Oncogene?