Bruno Pougault: Evidence-Based Guidance for Perioperative Bleeding Management
Bruno Pougault, Global Marketing Hemostasis Product Manager at HORIBA ABX SAS, shared a post on LinkedIn about a recent article by Jerrold H. Levy et al, published in Journal of Thrombosis and Hemostasis:
” Advancing perioperative bleeding management through evidence and expert guidance
I am pleased to share this important new guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis, recently published in the Journal of Thrombosis and Haemostasis:
‘Use of factor concentrates for the management of perioperative bleeding: guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis‘.
Perioperative bleeding remains a major clinical challenge, particularly in cardiac surgery, trauma, obstetrics and organ transplantation. Its management is complex because acquired coagulopathy can involve multiple mechanisms, including blood loss, hemodilution, hypothermia, acidosis, fibrinolysis, inflammation, and consumption of coagulation factors and platelets.
From a scientific and laboratory perspective, this guidance is particularly relevant.
It highlights the growing role of coagulation factor concentrates within perioperative bleeding management algorithms, including their rapid availability, standardized dosing, lower infusion volumes and pathogen inactivation.
More broadly, it reinforces an important principle in modern hemostasis: managing major bleeding requires us to connect clinical assessment, timely coagulation testing and targeted therapeutic strategies.
This interaction between laboratory medicine and clinical decision-making is critical to help provide the right information, at the right time, to support the management of bleeding patients.
Many congratulations and sincere thanks to the authors and the ISTH SSC experts for bringing together the available evidence and their expertise in this valuable guidance for the thrombosis and hemostasis community.”
Title: Use of factor concentrates for the management of perioperative bleeding: guidance from the ISTH SSC Subcommittee on Perioperative and Critical Care Thrombosis and Hemostasis
Authors: Jerrold H. Levy, Joseph R. Shaw, Deborah M. Siegal, Jeannie Callum, Corinne Frere, Keyvan Karkouti, Cheryl L. Maier, Michael Mazzeffi, C. Marc Samama, Risa Shorr, Kenichi A. Tanaka, Cornelius M. Dyke, Jean M. Connor
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 29, 2026, 15:54Negar Saleh: Integrating Interpretability Into AI-Based Pulmonary Embolism Prediction
-
Oct 29, 2026, 15:53Shweta Tikoo: New Pathways of Macrophage Development From Embryonic Life to Adulthood
-
Oct 29, 2026, 15:40Daniel Messiha: AI-Integrated PERT Workflow Improves Pulmonary Embolism Care and Speeds Up Intervention
-
Oct 29, 2026, 15:36Brigitta Nicorici: Pregnancy and Laboratory Medicine
-
Oct 29, 2026, 15:22Ugo Clinton։ Tranexamic Acid From Discovery to a Life-Saving Treatment
-
Oct 29, 2026, 15:01Owen McCarty: Targeting FXI and FXII to Reduce Device-Associated Thrombosis and Inflammation
-
Oct 29, 2026, 14:47Ingeborg Hers: Exploring New Frontiers in Platelet Biology and Thrombosis Research
-
Oct 29, 2026, 14:36Theodore Iwashyna: Could Hemoglobin Thresholds Lead to Unnecessary Blood Transfusions in ICU Patients?
-
Oct 29, 2026, 14:24Aryabhatta Sadhu: Contributing to Nepal’s First CAR-T Cell Therapy Case