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How Antiseizure Medication Selection May Influence DOAC Safety in Epilepsy – JAMA Neurology
Oct 31, 2026, 19:40

How Antiseizure Medication Selection May Influence DOAC Safety in Epilepsy – JAMA Neurology

JAMA Neurology shared a post on LinkedIn about a recent article by Kai Michael Schubert et al., adding:

“Among adults with Epilepsy receiving direct oral anticoagulants, antiseizure medication selection was associated with different risks of thromboembolic events, major bleeding, and all-cause mortality.

Antiseizure medication choice may be a modifiable contributor to safety outcomes during anticoagulation and may inform treatment selection when seizure therapy and anticoagulation are both required.”

Title: Safety of Antiseizure Medications During Direct Oral Anticoagulant Therapy in Epilepsy

Authors: Kai Michael Schubert, Carolina Ferreira-Atuesta, Arunachalam Soma, Johan Zelano, David J. Seiffge, Francesco Brigo, Eugen Trinka, Nishant K. Mishra, Emilio Russo, Gregory Y. H. Lip, Gashirai K. Mbizvo, Marian Galovic

JAMA Neurology

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