Mugthalana Allet: The Role of Ubiquitin-Mediated Regulation in Platelet Function
Mugthalana Allet, PhD Researcher at Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Platelets Journal, adding
“I’m really happy to share that my first first-author literature review, titled ‘Mechanistic Insights into Ubiquitin-Mediated Regulation of Platelet Function’, has been published in Platelets Journal by Taylor and Francis Group!
Growing evidence shows that platelet activation is associated with changes in the ubiquitination profiles of platelet proteins and increased proteasome activity.
With increasing interest in targeting the ubiquitin pathway for the treatment of various disorders, understanding these mechanisms has become increasingly important.
In this review, we explore the current understanding of ubiquitin-mediated regulation of platelet signalling and activation, highlighting emerging mechanistic insights and key areas for future investigation.
Having presented a talk related to this topic in September at The Platelet Society meeting, it’s exciting to now see the work published!
It’s been a really valuable learning experience, and I’m incredibly grateful to everyone who has supported and guided me along the way.
A special thank you to my co-authors, Amanda Unsworth, Jon Humphries and Khalid Naseem, for their invaluable contributions, support and collaboration throughout this work!”
Title: Mechanistic insights into ubiquitin-mediated regulation of platelet function
Authors: Mugthalana Allet, Jon D. Humphries, Khalid M. Naseem, Amanda J. Unsworth
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