November 2026
M	T	W	T	F	S	S
	1
2	3	4	5	6	7	8
9	10	11	12	13	14	15
16	17	18	19	20	21	22
23	24	25	26	27	28	29
30

Deniz Aslan: Advancing Pediatric Beta-Thalassemia Screening

Deniz Aslan//www.researchgate.net

Nov 14, 2026, 13:58

Deniz Aslan: Advancing Pediatric Beta-Thalassemia Screening

Deniz Aslan, Professor of Pediatrics and Hematology at Gazi University’s School of Medicine, shared a post on LinkedIn:

“At the 2nd International Congress of the Turkish National Pediatric Association, I shared our latest findings on a critical screening challenge: detecting Beta-Thalassemia Trait (BTM) when coexisting with Iron Deficiency (ID) in children.

When ID and BTM overlap, standard Complete Blood Count (CBC) indices can easily fail. In fact, our study showed that classical discrimination formulas (such as England & Fraser, Green & King, and Srivastava) miss up to 25–30% of BTM carriers due to this masking effect.

A few clear clinical takeaways from our evaluation:

Which formulas work: Shine & Lal, Hameed, and SVM-based machine learning models showed 100% sensitivity—remaining fully resilient even in the presence of iron deficiency.

When to avoid classical formulas: In severe pediatric anemia (Hb<9 g/dL), classical formulas lose reliability and shouldn’t be used for screening.

The power of HIS integration: By embedding iron-resilient formulas or SVM models directly into Hospital Information Systems (HIS), we can generate automatic CBC report alerts—catching BTM early at zero extra cost to the health system.

Integrating these smart screening alerts into routine lab workflows can significantly reduce diagnostic delays in endemic areas.”

Deniz Aslan: Advancing Pediatric Beta-Thalassemia Screening Stay updated with Hemostasis Today.