Aryabhatta Sadhu: Irradiation of Blood Components – From Clinical Indication to Laboratory Release
Aryabhatta Sadhu, Attending Consultant and Head of Transfusion Medicine at Fortis Hospital Shalimar Bagh, New Delhi, Member of AABB, Member International Society of Blood Transfusion (ISBT), shared a post on LinkedIn:
“Irradiation of blood components: from clinical indication to laboratory release
Preventing transfusion-associated graft-versus-host disease (TA-GVHD) requires timely identification of patients who need irradiated cellular components. Irradiation prevents donor T-lymphocyte proliferation; leukoreduction does not provide equivalent protection.
I have prepared these two infographics as a practical reference for clinicians and transfusion laboratory teams.
The clinical poster addresses indications, component selection and situations in which irradiation is not routinely required. The laboratory poster covers dose requirements, process validation, quality control, traceability, storage restrictions and processing costs.
The material draws on AABB, British Society for Haematology, NHS Blood and Transplant, and WHO resources. American and European requirements are distinguished where they differ, particularly for dose specifications and post-irradiation red-cell storage.
In practice, the challenge extends beyond delivering the prescribed radiation dose. Treatment history must be available, irradiation requirements must remain visible across admissions, and the correct component must reach the patient within its revised expiry.
These summaries are intended to support clinical discussion, staff training and review of institutional irradiation policies. They should be used alongside locally approved protocols and component specifications.”
Other posts featuring Aryabhatta Sadhu on Hemsotasis Today.
-
Oct 19, 2026, 08:20Cory Dugan: The IRONWOMAN Trial Individual Responses to IV Iron Therapy in Active Women
-
Oct 19, 2026, 07:36Johannes Kaesmacher: Cerebral No-Reflow After Thrombectomy Toward a Standardized Definition
-
Oct 19, 2026, 07:33Beth Psaila: Highlights from IACH Annual Meeting and MPN Horizons
-
Oct 19, 2026, 07:29Wolfgang Miesbach: Can Losartan Activate Brown Fat? – Nature Study Explores New Therapeutic Link
-
Oct 19, 2026, 07:22Ruben Mesa: Honored to Speak at the Tandem MPN Meetings of IACH
-
Oct 19, 2026, 07:19Saneha Anjum Shaikh: Parul University Partners with Raktasevak Bike Ride 2026 for Blood Donation Drive
-
Oct 19, 2026, 07:09Alejandro González Veliz: No ST Elevation Does Not Guarantee an Open Coronary Artery
-
Oct 19, 2026, 06:02Thomas Dayspring: Vascular Resilience – What Is It and How Can We Measure It?
-
Oct 19, 2026, 05:53Kevon Dindial: Collaboration for Better Childhood Cancer OutcomesÂ